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Primary Malignant Melanoma of Female Urethra: A Case Report and Review of Literature

Authors

  • Shashank Agrawal Email MBBS, MS, DNB(UROLOGY)
  • Tak GR MBBS, MS, DNB(UROLOGY)
  • Aditya Parikh MBBS, MS, DNB(UROLOGY)
  • Arvind Prakash Ganpule MBBS, MS, DNB, MNAMS (Vice Chairman)
  • Abhishek Gajendra Singh MBBS, MS, M.ch, DNB
  • Ravindra Bhalchandra Sabnis MBBS, MS, Mch (Chairman)
  • Mahesh Ramanlal Desai MBBS, MS, FRCS, FRCS (Medical Director)

DOI:

https://doi.org/10.30564/jor.v1i3.1975
Received: 10 June 2020 | Published Online: 3 July 2020

Abstract

We report a very rare case report of female diagnosed with primary ma
lignant melanoma. A 65 years old diabetic elderly postmenopausal female
presented with a history of intermittent blood spots on undergarments for
few days. Genital examination revealed a single, tan colored, soft chest
nut size and polypoidal non ulcerated mass lesion protruding through the
urethral meatus. Mass biopsy revealed poorly differentiated epithelial ma
lignancy and immuno-histological analysis revealed positive with HMB
45 and protein S-100 suggestive of melanoma. Metastatic work up for the
malignancy was negative. Complete urethrectomy with Mitrofanoff pro
cedure with inguinal lymph node dissection was performed. Histopatho
logical examination was suggestive of malignant melanoma of urethra.
Here we discuss the clinicopathological features and management option
possible in this scenario.

Keywords:

Female, urethra, melanoma

References

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Issue

2019 Vol.1 No.3

Article Type

Article

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Copyright © 2020 Shashank Agrawal, Tak GR, Aditya Parikh, Arvind Prakash Ganpule, Abhishek Gajendra Singh, Ravindra Bhalchandra Sabnis, Mahesh Ramanlal Desai

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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.