Abstract: Cancer is a devastating disease that suffered so many lives and families throughout of the world, and is becoming an increasing burden to our society. Thanks to the advances in both basic cancer biology and clinical diagnostic/therapeutic treatments, cancer patients’ mortality has been significantly decreased in the past decades. Specifically, recent breakthrough in cancer immunology and immunotherapy has shed a bright light for cancer patients... More

Abstract: The Aryl hydrocarbon receptor (AhR) ligands exhibiting modulating activity represents a new class of anticancer agents that can be directed towards several tumors. We have examined AhR expression in human colon cancer and adjacent non-tumor tissue. AhR expression level was about 2-7 times higher in tumor tissue samples than in the adjacent non-tumor samples (in 82% of all the samples). We were unable to find any increase of ABCG2 expression on... More

Abstract: Objectives: To explore the clinical effect of psychological intervention and nursing during the chemotherapy of gynecological malignant tumor. Methods: 120 patients with gynecologic malignancies were selected as subjects. According to the nursing method, these patients were divided into intervention group and control group, with 60 cases in each group. The patients in the control group were given routine care, and the patients in the observation... More

Abstract: In recent years, treatment methods on immune checkpoints have emerged as promising novel therapeutic modalities against cancer as a result of studies focusing on elucidation of immune micro-environment. Immunotherapy has now become an established treatment in some cancers. [1-2] This has led the need for investigation of biomarkers which allow determining effectiveness of immunotherapies and patient groups which will most benefit from these... More