Welcome to Bilingual Publishing Group

A Royal Jelly Mixture with Berberine for Dressing Change on a Refractory Skin Ulcer: A Case Report

Authors

  • Weisheng He No.2 Department of Geriatrics, Hangzhou Wenzhong Hospital, Hangzhou, 310000, China
  • Mimi Zhou Email No.2 Department of Geriatrics, Hangzhou Wenzhong Hospital, Hangzhou, 310000, China
  • Yue Chen No.2 Department of Geriatrics, Hangzhou Wenzhong Hospital, Hangzhou, 310000, China

DOI:

https://doi.org/10.30564/jgm.v3i2.3472
Received: 18 July 2021 | Published Online: 8 October 2021

Abstract

It has been reported that a 92-year-old female had got a bruise superficial
wound on her right leg one and a half years ago, developing into refractory
skin ulcer due to improper management before. A prepared cream, mixed
royal jelly with berberine for dressing change, was made on the scene
through the crush of berberine tablets, working with fresh royal jelly.
Topical dressing change with the cream was done every 3 days, and two
months later, such the ulcer became clean and was covered fully with fresh
granulation tissue. This kind of cream consists of the ingredients of TCM
purely, free of antibiotic, and being quite effective clinically, also helpful
for proper use of antibiotic.

Keywords:

Refractory skin ulcer, A mixture of TCM dressing change, Proper use of antibiotic

References

[1]Fratini F, Cilia G, Mancini S(2016) Royal Jelly: An ancient remedy with remarkable antibacterial properties. Microbiol Res 192:130-141.

[2]AM Ali, H Kunugi(2020) Apitherapy for age-related skeletal muscle disfunction(sarcopenia): A review on the effects of royal jell, propolis, and bee pollen. Foods 9:1362-1365.

[3]Butler E, Oien R F, Lindholm C(2016) A pilot study investigating lactic acid bacterial symbionts from the honeybee in inhibiting human chronic wound pathogens. Int Wound J 13:729-737.

[4]Daniele G, Casabianca H(2012) Sugar composition of French royal jelly for comparison with commercial and artificial sugar samples. Food Chem 134:1025-1029.

[5]Alvarez-Suarez J M, Giampieri F, Battino M(2013) Honey as a source of dietary antioxidants: structures, bioavailability and evidence of protective effects against human chronic diseases. Curr Med Chem, 20:621-638.

[6]Wang Y, Wen B, Yu H(2018) Berberine Hydrochloride-Loaded Chitosan Nanoparticles Effectively Targets and Suppresses Human Nasopharyngeal Carcinoma. Journal of Biomedical Nanotechnology 14:512-517.

[7]Dan Y, Xiaohe X, Cheng J(2008) Microcalorimetric investigation of the effect of berberine alkaloids from Coptis chinensis Franch on Staphylococcus aureus growth. Science in China Series B: Chemistry 51:1026-1030.

[8] Kwakman P H, de Boer L, Ruyter-Spira C P(2011) Medical-grade honey enriched with antimicrobial peptides has enhanced activity against antibiotic-resistant pathogens. Eur J Clin Microbiol Infect Dis, 30:251-257.

Downloads

Issue

Article Type

Case Report